Mfn2 antibody cst
WebbProtein Mutation Frequency in Cancer. The 'lollipop plot' above illustrates recurrent (observed in 3 or more out of 4440 TCGA tumor samples from 15 cancer types) and therefore potentially oncogenic missense mutations (click on 'Show Cancer Mutations'). The bar plot below shows the proportion of tumor samples that have any kind of altering ... Webb25 juli 2024 · In order to research the protective effect of Mfn2 on dopaminergic neurons, Santa Cruz Biotechnology MFN2 antibody (SantaCruz, sc-100560) was used in western blot on mouse samples (fig 4a) and in western blot on human samples (fig 1a). Biochim Biophys Acta Mol Basis Dis (2024) ncbi. mouse monoclonal (XX-1) sc-100560.
Mfn2 antibody cst
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Webb12 jan. 2024 · Biochemical analysis revealed that MFN2 mutations are diverse 19, making collective targeting of all MFN2 defects mechanistically challenging. Here we report a small molecule agonist of... WebbProtein Mutation Frequency in Cancer. The 'lollipop plot' above illustrates recurrent (observed in 3 or more out of 4440 TCGA tumor samples from 15 cancer types) and …
WebbAntibody specificity analysis with protein arrays. Predicted and matching interactions are shown in green. N/A. Antibody dilution: 1:3000: RELEVANT PUBLICATIONS; Bit-by … WebbMFN2 Antibody (12186-1-AP) in IHC (P) Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using (Product # 12186-1-AP) (MFN2 …
WebbMonoclonal Antibody for studying COX IV. Cited in 490 publications. Validated for WB, IP, IHC, IF, F. Available in 2 sizes. Highly specific … WebbAntibodies that detect MFN2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target MFN2 in Human, Rat and Mouse samples.
Webb20 dec. 2024 · The endoplasmic reticulum (ER) stress and mitochondrial dysfunction in high glucose (HG)-induced podocyte injury have been demonstrated to the progression of diabetic kidney disease (DKD). However, the pathological mechanisms remain equivocal. Mitofusin2 (Mfn2) was initially identified as a dynamin-like protein involved in fusing the …
WebbMFN2, also named as CPRP1 and KIAA0214, belongs to the mitofusin family. It is an Essential transmembrane GTPase, which mediates mitochondrial fusion. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. shipman elementary school shipman ilWebb12 maj 2024 · Mfn2 is sulfenylated during inflammation and accumulates in the nucleus where it acts as an endogenous suppressor of inflammation by binding the transcriptional regulator β-catenin. Mfn2 binds... shipman doctorWebbIn cells expressing Myc-MFN2, co-immunoprecipitation experiments showed that endogenous AMPKα1, rather than β1 or γ1, is present in the MYC-MFN2 complex precipitated using an anti-Myc antibody . Conversely, endogenous MFN2 was co-precipitated by an anti-HA antibody in cells are expressing HA-AMPKα1 ( Figure 4B ). quarter sawn maple lumber for salequarter sawn hickory lumberWebbMonoclonal Antibody for studying Mitofusin-2. Cited in 200 publications. Validated for WB, IHC, IF. Highly specific and rigorously validated in … quarter sawn heart pineWebb9 aug. 2024 · Mfn2 Antibody (F-5) is an IgG 1 κ mouse monoclonal Mfn2 antibody (also designated mitochondrial membrane protein Mfn2 antibody, mitochondria marker … quarter sawn oak bathroom vanityWebbThe presentation of p-DRP1 and MFN2 was markedly reduced in the OGD/R group, which was restored by pretreatment with curcumin (10, 20, and 40 μM) (Figures 6(d)–6(g)). In the OGD/R group, mitochondrial swelling and loss of cristae were observed using a TEM, while pretreatment with curcumin (10, 20, and 40 μ M) attenuated these morphological … shipman dr death