Shumiya cataract rat

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August undefined, 2024

WebLens reconstruction after mature cataract in SCR rat. @article{Okano1999LensRA, title={Lens reconstruction after mature cataract in SCR rat.}, author={Takuya Okano and Shigekazu Uga and S. Ishikawa and Akiko Hara and Seigou Shumiya}, journal={Japanese journal of ophthalmology}, year={1999}, volume={43 5}, pages={ 363-7 } } WebThe Shumiya cataract rat (SCR) is a hereditary cataractous strain. It is thought that the continuous occur-rence of poorly differentiated epithelial cells at the bow area of the lens …

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WebApr 1, 2007 · Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the Shumiya cataract rat. Mori M, Li G, Abe I, Nakayama J, Guo Z, Sawashita … WebA new cataractous rat strain, Shumiya Cataract Rat (SCR), which was derived from the cross-breeder formed between the spontaneous hypertensive rat and the Zucker fatty rat, … how to select sunscreen for kids

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Webcataract drug for human cataracts has not yet been intro-duced. In studies to develop anti-cataract drugs, the selection of the experimental animal is very important. The UPL rat (UPLR), Shumiya cataract rat (SCR) and Ihara cataract rat (ICR/f; ICR) are hereditary cataractous strains, and it has been shown that these rats provide useful models ... http://www.anim.med.kyoto-u.ac.jp/model/shumiya/SCR.html WebFeb 1, 2024 · @article{Nagai2024TheII, title={The Intravitreal Injection of Lanosterol Nanoparticles Rescues Lens Structure Collapse at an Early Stage in Shumiya Cataract Rats}, author={Noriaki Nagai and Yuya Fukuoka and Kanta Sato and Hiroko Otake and Atsushi Taga and Mikako Oka and Noriko Hiramatsu and Naoki Yamamoto}, journal={International … how to select text box on photoshop

Histopathological study of hereditary cataractous lenses in SCR …

Functional polymorphisms of the Lss and Fdft1 genes in …

WebPurpose: To conduct a long-term observation study of SCR rats that had developed a mature cataract at 11 weeks of age at 3-month intervals until the rats were 12 months old. Methods: Lenses of 15 rats were examined with both light and electron microscopes.. Results: At 12 weeks, opacity was observed in the perinuclear zone and the cortical intermediate layer. WebAug 20, 2024 · The lens of cataract rats had α-A crystallin expression levels increased by 35% when compared to the control (Fig. 2E). ... Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the Shumiya cataract rat. J. Clin. Invest., 116 (2006), pp. 395-404. CrossRef View Record in Scopus Google Scholar how to select tax regime in itrWebNov 2, 2024 · The Shumiya cataract rat (SCR) is a model for hereditary cataract. Two-thirds of these rats develop lens opacity within 10-11 weeks. Onset of cataract is attributed to … how to select tennis strings

"WebSix-week-old Shumiya cataract rats were used to perform experiments. The right eye of each rat was injected with TAT-HA-Prdx6 WT-NPs or TAT-HA-Prdx6 K122/142R-NPs, whereas the left eyes were administered with TAT-HA-Prdx6 Inactive-mutant-NPs. The subconjuctival injection was made using micro-syringes fitted with 30-gauge needles. " - Shumiya cataract rat

Shumiya cataract rat

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WebWe discovered that the cataract development in the Shumiya cataract rat (SCR) can be prevented by the administration of deep-sea drinking water (DDW). A standard diet based … WebMar 29, 2005 · Cataract onset is associated with the specific combination of Lss and Fdft1 mutant alleles that decrease cholesterol levels in cataractous lenses to about 57% of normal. Cholesterol insufficiency may cause the deficient proliferation of lens epithelial cells in Shumiya cataract rats, resulting in the loss of homeostatic epithelial cell control of the …

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WebDelay of cataract development in the Shumiya cataract rat by water containing enhanced concentrations of magnesium and calcium Curr Eye Res. 2007 May;32(5):439-45. doi: … WebOct 25, 2024 · By positional cloning and genotyping in Shumiya cataract rats, Mori et al. (2006) identified hypomorphic mutations in the Lss gene and the Fdft1 gene, as well as a null mutation in Lss.Cataract onset was associated with the specific combination of Lss and Fdft1 mutant alleles that decreased cholesterol levels in cataractous lenses to about 57% …

WebOct 1, 2001 · Aminoguanidine-treatment results in the inhibition of lens opacification and calpain-mediated proteolysis in Shumiya cataract rats (SCR). Inomata M, Hayashi M, … WebInomata M, Hayashi M, Shumiya S, Kawashima S, Ito Y. Aminoguanidine-treatment results in the inhibition of lens opacification and calpain-mediated proteolysis in Shumiya Cataract Rats (SCR). J Biochem. 2000;128(5):771–776. 41.

WebWe previously found that the increases in Ca 2+ content in the lenses of three hereditary cataract model rats, UPL rat (UPLR), Shumiya cataract rat (SCR) and Ihara cataract rat (ICR), are inhibited by aminoguanidine, a selective inhibitor of inducible nitric oxide synthase, and that the mechanisms of Ca 2+ enhancement in these rat models differ. In this study, we … WebJul 4, 2024 · The Shumiya cataract rat (SCR) is a hereditary cataractous rat strain, which is classed as two models (non-cataract type, SCR-N, and cataractous type, SCR-C) . SCR-N (ctr1 × ctr1, Ctr2 × Ctr2), without the mutations causing premature cataracts, maintains a transparent lens, although slight lens structure collapse was observed at 8–12 weeks of …

WebNov 1, 1993 · The Shumiya cataract rat (SCR) is a hereditary cataract model in which lens opacity appears spontaneously in the nuclear and perinuclear portions at 11–12 weeks of …

Web开馆时间：周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 how to select table range in excelWebApr 7, 2024 · By positional cloning and genotyping in Shumiya cataract rats, Mori et al. (2006) identified hypomorphic mutations in the Lss gene and the Fdft1 gene (), as well as a null mutation in Lss.Cataract onset was associated with the specific combination of Lss and Fdft1 mutant alleles that decreased cholesterol levels in cataractous lenses to about 57% … how to select tabs on excelWebFeb 1, 2006 · The Shumiya cataract rat (SCR) and normal control rat strains of NC1 and NC2 were established. Mean cataract appearance in adult SCR rats was 66.7%, and embryo … how to select tennis grip sizeWebThe Shumiya cataract rat (SCR) is a hereditary cataractous strain. It is thought that the continuous occur-rence of poorly differentiated epithelial cells at the bow area of the lens forms the pathophysiological basis for cataract formation in SCRs. In this study, we attempted to identify the genes associated with cataract how to select task viewWebJun 1, 2006 · Search life-sciences literature (Over 39 million articles, preprints and more) how to select telescopeWebJul 10, 2003 · Methods Selenite cataract was induced in Sprague–Dawley rats by five subcutaneous injections of sodium ... activity in selenite nuclear cataract 20 and Shumiya cataract 21 in rat. ... how to select target window in bandicamWebShumiya cataract rat (SCR) is a hereditary cataractous rat strain that develops cataract at approximate 11 weeks of age . Lss gene is mutated in SCR and is the major gene for cataract onset [ 19 ]. In humans, two distinct homozygous LSS missense mutations (W581R and G588S) happen in two families with extensive congenital cataracts, which impairs key … how to select tablet mode